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1994年9月,25(9):915 - 9。
0046 - 8177 . doi: 10.1016 /(94) 90011 - 6。

幽门螺杆菌感染的胃贲门

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幽门螺杆菌感染的胃贲门

R M Gentaet al。 哼分册 1994年9月

摘要

幽门螺杆菌胃炎被认为在胃窦比在身体更普遍和更严重。贲门粘膜在结构上与前庭粘膜相似。本研究旨在验证这样一种假设,即幽门螺杆菌感染的强度和相关炎症在贲门和前庭相似,并且在这些位置比在身体中更大。共从50名受试者(42例有幽门螺杆菌感染)的预定部位获得445份胃活检标本。用联合染色同时观察幽门螺旋杆菌、黏膜形态和炎症浸润。幽门螺杆菌、炎症反应和肠化生的数量从0到5进行分级。42名感染者中有40人(95%)的心脏被检测出幽门螺杆菌。3个胃区幽门螺杆菌密度相似。慢性活动性胃炎在胃窦和贲门的强度相似,且在这些部位高于主体(P < .005)。淋巴滤泡在贲门和体中明显少于前庭(P < 0.05)。 Helicobacter pylori infection was as prevalent in the cardia as in the rest of the stomach and its density was similar in all sites of antrum, corpus, and cardia. The inflammatory responses characteristic of chronic active gastritis, except for lymphoid follicles, were similar in the antrum and the cardia and in both these locations were more intense than in the corpus. The significance of these findings is discussed with respect to the relationship between H pylori infection and the genesis of gastric adenocarcinoma and lymphoma.

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