文摘

弯曲杆菌的发生幽门(CP)对179名受试者的研究代表一个样本来自芬兰南部的人口。正常窦性和身体黏膜CP存在于5%和11%在浅表胃炎(SG)在71%和91%的受试者,分别。萎缩性胃炎(AG)的腔和身体CP的患病率与越来越萎缩程度显著降低,这样CP不存在严重的身体。窦的和身体的不同组合胃炎显示特征模式。弯曲杆菌缺乏幽门窦的和身体黏膜正常时,但有41%正常粘膜与胃炎相反的区域。SG影响扩散腔和身体的细菌存在于每一个案例中,但当SG与AG)相反的区域缺乏29%的受试者。当SG影响这两个方面与SG伴随着不同程度的AG)在体内,有一个高度明显降低CP在腔和身体的患病率增加程度的AG)在体内。这种减少呈高度显著正相关与酸产量。总的来说,酸产量相关与CP的发生在两个腔和身体。因此在胃酸缺乏症CP的患病率是10%,上涨100%的情况下酸产量超过30更易与h。 The presence of CP did not correlate with signs of acute inflammation, but correlated significantly with those of chronic inflammation. No correlation was found in the antrum and a significant negative one in the body, between CP infestation and the extension of intestinal metaplasia. It is concluded that increased pH of gastric contents and mucus secreted by intestinalised glands may create unfavourable conditions for survival of the bacteria and might explain the decrease in the prevalence of CP in the more severe degrees of AG. The present results, however, give no definite answer to the question of the pathogenic significance of CP in the development of chronic gastritis.