摘要

胃食管反流和哮喘之间的确切关系尚不清楚。为了确定哮喘患者胃食管反流是否会导致食管炎，我们对186例连续成人哮喘患者进行了内镜检查和食管活检。有无返流症状不作为哮喘的选择标准。内窥镜检查由两名内窥镜医生使用预先确定的标准进行。所有哮喘患者均有离散性喘息，既往有哮喘诊断或有记录的可逆转气道阻塞至少20%。食管管状食管内无糜烂或溃疡，食管黏膜分级正常;如食管炎，有渗出物的粘膜破裂(糜烂和/或溃疡)存在;Barrett's if特化(肠)柱状上皮存在。如果在内镜检查中膈上方出现大于或等于2厘米的胃粘膜，则诊断为裂孔疝。39%的哮喘患者患有食管炎或巴雷特食管，或两者兼有。 There was no difference in the oesophageal mucosal status between asthmatics who required and those who did not require bronchodilators. Fifty eight per cent of asthmatics had a hiatal hernia. It is concluded that oesophagitis is common and independent of the use of bronchodilator therapy in asthmatics.