摘要

对1975年至1988年间利兹总医院食管癌的治疗进行了综述。所有经组织学证实为食管癌的病例均纳入研究，数据来源于病例记录、手术室手术记录、内窥镜检查记录、病理记录和约克郡癌症登记处。316名患者被确诊。将人口学细节、表现方式、术前调查、手术处理、姑息治疗方法和生存数据输入数据库。男女比例为3:2，发病年龄中位数为69岁(35-96岁)。316例患者中134例(42%)进行了手术探查。134例患者中有106例(79%)可以切除肿瘤，无论是根治性的还是姑息性的。手术(30天)死亡率为27%。134例患者中有22例(16%)只能进行肿瘤插管，而6例(5%)仅进行了开胸或剖腹手术。106例患者手术切除后的中位生存期为292天(范围0-14.2年)，其中7例(7%)在5年后仍然存活。 Of the remaining 182 patients (58%) who were not operated upon, 36 patients (11%) had a radical course of radiotherapy with a median survival of 175 days (range 80-453) and 146 patients (46%) either had endoscopic intubation (n = 64) or received no specific treatment (n = 82) with a median survival of 106 days (1-725) and 91 days (1-358) respectively. None of the 182 patients who did not have surgical treatment was alive at five years.