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  • Advanced paternal age increases risk of bipolar disorder in offspring
    Free
    ...QUESTION Question: Doesadvancedpaternal age increase the risk of bipolar disorder in offspring? People: 7 739 202 individuals were identified through linkage of the Hospital Discharge Register and the Multigeneration Register. From this study base of over 7 million individuals, 13 428 cases (42 ...
  • EmerJoyce,VictoriaDelgado,Jeroen JBax,Nina AjmoneMarsan
    Advanced techniques in dobutamine stress echocardiography: focus on myocardial deformation analysis
    Free
    ...the ischaemic cascade at an earlier stage than that represented by an induced wall motion abnormality. The aim of the current article is thus to summarise both established and emergingadvancedtechniques to improve the accuracy of stress echocardiography in its main roles of ischaemia detection and viability ...
  • Philipp SMuether,AngelaKribs,MoritzHahn,JasminSchumacher,FrankEifinger,BerndKirchhof,BernhardRoth,SaschaFauser
    No advanced retinopathy of prematurity stages 4 or 5 in a large high-risk German cohort
    .... Increasing treatment incidence was associated with lower GA, but not with lower BW in logistic regression analysis. Conclusion In this very immature high-risk cohort,advancedstages 4 and 5 were avoided throughout 9 years of screening. We suggest three factors that contributed to this outcome: (1) strict ...
  • RanjithRamasamy,Larry ILipshultz
    Mixed associations observed between advanced paternal age and psychiatric morbidity in offspring
    Free
    ...Ranjith Ramasamy, Larry I Lipshultz Department of Urology, Baylor College of Medicine, Houston, Texas, USA Correspondence to Larry I Lipshultz; larryl@bcm.edu WHAT IS ALREADY KNOWN ON THIS TOPIC?Advancedmaternal age has long been acknowledged as a risk factor for genetic disorders such as Down ...
  • Dementia in advanced age led to higher mortality rates and shortened life
    Free
    ...Prognosis AgeroTorres H, Fratiglioni L,Guo Z, et al.Mortality from dementia inadvancedage: a 5year followup study of incident dementia cases. J Clin Epidemiol 1999 Aug;52:73743. QUESTION: What is the mortality rate and survival time for patients with dementia inadvancedage, and does ...
  • KathrinRychli,BernhardRichter,Philipp JHohensinner,KariemMahdy Ali,StephanieNeuhold,GerlindeZorn,RudolfBerger,DeddoMörtl,KurtHuber,RichardPacher,JohannWojta,AlexanderNiessner,MartinHülsmann
    Hepatocyte growth factor is a strong predictor of mortality in patients with advanced heart failure
    ..., antiapoptotic, angiogenic and antifibrotic hepatocyte growth factor (HGF) in heart failure (HF). Design Prospective cohort study. Setting/patients Assessment of HGF levels at inclusion in 351 patients withadvancedHF (median 75 years, interquartile range (IQR) 63e82, 66% male). Main outcome measures All ...
  • R SGardner,WMartin,RCarter,T AMcDonagh
    Importance of β blockade in the treatment of advanced heart failure
    Free
    ...SCIENTIFIC LETTER Importance of b blockade in the treatment ofadvancedheart failure R S Gardner, W Martin, R Carter, T A Mc ...
  • Karen JHogg,Shona M M詹金斯
    Prognostication or identification of palliative needs in advanced heart failure: where should the focus lie?
    ...Karen J Hogg, Shona M M Jenkins Heart failure (HF) is a significant public health issue with high morbidity and mortality despite persistentadvancesin therapeutic strategies. HF is physically and psychologically burdensome for patients and their families and costly to the NHS; the latter driven ...
  • P EAntunes,J M Ferrãode Oliveira,M JAntunes
    有限公司ronary surgery with non-cardioplegic methods in patients with advanced left ventricular dysfunction: immediate and long term results
    Free
    ....3 4 In addition,advancesin surgical technique, perioperative care, and myocardial protection have enhanced the safety of CABG in this cohort of patients.59 Effective myocardial preservation is essential for successful CABG when the myocardium is handicapped. However, there is still controversy ...
  • MinakoKaido,MotokoKawashima,NorihikoYokoi,正树Fukui,YoshiyukiIchihashi,HiroakiKato,MotokoYamatsuji,MitsukoNishida,KazumiFukagawa,ShigeruKinoshita,KazuoTsubota
    Advanced dry eye screening for visual display terminal workers using functional visual acuity measurement: the Moriguchi study
    ...version of the DE screening method may be acceptable for practical use in VDT workers. INTRODUCTION Occupational health problems among office workers have become a subject of growing concern with the rapidadvancesin information technology and expanded use of visual display terminals (VDTs). VDT workers ...

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