摘要

直肠结肠切除并回肠袋吻合可通过梗阻或细菌过度生长两种机制改变小肠运动。对11例回肠吻合术后6个月(n = 6)或12个月(n = 5)行回肠吻合术的患者测量空肠运动。在禁食期间(4小时)和液体餐后(1小时)进行空肠测压记录。研究人员将这些结果与6名健康志愿者的结果进行了比较。运动事件分类如下:迁移运动复合体(MMC)，传播性收缩，或离散聚集性收缩。所有患者均接受细菌过度生长检查(d -葡萄糖呼气试验)。只有两名患者出现细菌过度生长。与正常志愿者(2.81(0.29)/ 4小时)相比，回肠肛管吻合后MMC发生率(2.83(0.37)/ 4小时)不变。禁食期间，4例患者空肠出现大量繁殖性收缩。这两种情况与细菌过度生长有关，两种情况与储液库插管有关。 Discrete clustered contractions were found in the seven patients studied postprandially (7.6 (2.5)/h), but not in volunteers. These seven patients emptied their pouch spontaneously and bacterial overgrowth was found in only one. As this motility pattern was previously described in partial small intestinal obstruction, it is postulated that discrete clustered contractions could be the consequence of a functional obstruction as a result of anastomosis of the small intestine to the high pressure zone of the anal sphincters.