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8,557 results
for term "advanced"
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Quantitation of faecalFusobacteriumimproves faecal immunochemical test in detecting advanced colorectal neoplasia...J Y Sung1,2,3 ABSTRACT Objective There is a need for an improved biomarker for colorectal cancer (CRC) andadvancedadenoma. We evaluated faecal microbial markers for clinical use in detecting CRC andadvancedadenoma. Design We measured relative abundance of Fusobacterium nucleatum (Fn ...
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Risk factors for advanced neoplasia within subcentimetric polyps: implications for diagnostic imaging...lesions. The aim of this study was to identify risk indicators foradvancedneoplasia (AN) in subcentimetric polyps. Design Colonoscopies were classified on the basis of the largest lesion found. AN was defined as high-grade dysplasia, villous histology, or cancer. Logistic regression models were ...
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A score to estimate the likelihood of detecting advanced colorectal neoplasia at colonoscopy...al. Gut 2014;63: 11121119. ABSTRACT Objective This study aimed to develop and validate a model to estimate the likelihood of detectingadvanced白种人患者结直肠肿瘤。设计We performed a cross-sectional analysis of database records for 40-year-old to 66-year-old patients who ...
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Thiopurines prevent advanced colorectal neoplasia in patients with inflammatory bowel disease...with inflammatory bowel disease (IBD). This effect has not been reported in IBD patients using thiopurines. We investigated the association between thiopurine or 5-ASA use and the risk ofadvanced瘤(一个),including high-grade dysplasia and colorectal cancer, in a large cohort of patients with IBD ...
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Prediction of proximal advanced neoplasia: a comparison of four existing sigmoidoscopy-based strategies in a Chinese population...MCS, Ching JYL, Ng SC, et al. Gut 2015;64:776783. ABSTRACT Objective To compare the performance of existing sigmoidoscopy-based strategies in predictingadvancedproximal neoplasia (APN) in an asymptomatic Chinese cohort. Design We included all screening participants aged 5070 years who received ...
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Safety and on-treatment efficacy of telaprevir: the early access programme for patients with advanced hepatitis C...ORIGINAL ARTICLE Safety and on-treatment efficacy of telaprevir: the early access programme for patients withadvancedhepatitis C M Colombo,1 I Fernández,2 D Abdurakhmanov,3 P A Ferreira,4 S I Strasser,5 P Urbanek,6 C Moreno,7 A Streinu-Cercel,8 A Verheyen,9 W Iraqi,10 R DeMasi,11 A Hill,12 J M ...
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MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model...is a recipient of an Intra-European Marie Curie (FP7-PEOPLE-2009-IEF, Imaging Lymphoma) fellowship and a Long-term European Molecular Biology Organization (EMBO-ALT-1145-2009) fellowship. EMS and JA acknowledge the educational support of Programme forAdvancedMedical Education from Calouste Gulbenkian ...
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Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study...Objective For patients with locallyadvancedrectal cancer (LARC), adjuvant chemotherapy selection following surgery remains a major clinical dilemma. Here, we investigated the ability of circulating tumour DNA (ctDNA) to improve risk stratification in patients with LARC.Design We enrolled patients with LARC (T3/T4 and ...
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Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia...) and mucinous cystic neoplasms (MCNs), while TP53/PIK3CA/PTEN alterations are associated withadvancedneoplasia. A prospective study was performed to evaluate preoperative PCF DNA testing.Design Over 43-months, 626 PCF specimens from 595 patients were obtained by endoscopic ultrasound (EUS)-fine needle ...
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Statins reduce the progression of non-advanced adenomas to colorectal cancer: a postcolonoscopy study in 187 897 patients...on colorectal adenoma development, we also compared adenoma development (including any adenoma, non-advancedadenoma andadvancedadenoma) after index colonoscopy between statin users and non-users. Any adenoma encompassed both non-advancedandadvancedadenoma (defined as adenoma with severe dysplasia ...
